Газета «Новости медицины и фармации» Гастроэнтерология (553) 2015 (тематический номер)
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ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury
Авторы: Naga P. Chalasani, MD, FACG (1), Paul H. Hayashi, MD (2), Herbert L. Bonkovsky, MD, FACG (3), Victor J. Navarro, MD (4), William M. Lee, MD, FACG (5), Robert J. Fontana, MD (6), от лица Practice Parameters Committee of the American College of Gastroenterology
(1) — Indiana University School of Medicine, Indianapolis, Indiana, USA
(2) — University of North Carolina, Chapel Hill, North Carolina, USA
(3) — CarolinasHealthCare System, Charlotte, North Carolina, USA
(4) — Einstein Health Care Network, Philadelphia, Pennsylvania, USA
(5) — University of Texas at Southwestern Medical Center, Dallas, Texas, USA
(6) — University of Michigan, Ann Arbor, Michigan, USA
Рубрики: Гастроэнтерология
Разделы: Справочник специалиста
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Статья опубликована на с. 45-56
Idiosyncratic drug-induced liver injury (DILI) is a rare adverse drug reaction and it can lead to jaundice, liver failure, or even death. Antimicrobials and herbal and dietary supplements are among the most common therapeutic classes to cause DILI in the Western world. DILI is a diagnosis of exclusion and thus careful history taking and thorough work-up for competing etio–logies are essential for its timely diagnosis. In this ACG Clinical Guideline, the authors present an evidence-based approach to diagnosis and management of DILI with special emphasis on DILI due to herbal and dietary supplements and DILI occurring in individuals with underlying liver disease.
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